It is in the default mode and the I am not using the alert pin. Is it necessary? I am able to get a pretty consistent reading now based on the variance equation.I use 1600 samples per second. That gives me 16 samples in each half-cycle of 50Hz mains, and it can read the mains voltage accurate to 0.1V using a 12-bit A/D.
Are you using continuous conversion mode, and the alert/ready pin to determine when to read the new data?