Coronavirus?!

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nsaspook

Joined Aug 27, 2009
16,328
We are already at work with 2nd wave vaccines to counter harmful replications when they happen.

https://www.nature.com/articles/s41591-021-01230-y/figures/1

41591_2021_1230_Fig1_HTML.png

https://www.nature.com/articles/s41591-021-01230-y
Abstract
After the recent announcement of COVID-19 vaccine efficacy in clinical trials by several manufacturers for protection against severe disease, a comprehensive post-efficacy strategy for the next steps to ensure vaccination of the global population is now required. These considerations should include how to manufacture billions of doses of high-quality vaccines, support for vaccine purchase, coordination of supply, the equitable distribution of vaccines and the logistics of global vaccine delivery, all of which are a prelude to a massive vaccination campaign targeting people of all ages. Furthermore, additional scientific questions about the vaccines remain that should be answered to improve vaccine efficacy, including questions regarding the optimization of vaccination regimens, booster doses, the correlates of protection, vaccine effectiveness, safety and enhanced surveillance. The timely and coordinated execution of these post-efficacy tasks will bring the pandemic to an effective, and efficient, close.
 

SamR

Joined Mar 19, 2019
5,491
For the most part, it's not the teachers. They don't get any say in school board policies and procedures that they are forced to adhere to or else. Dictatorial policies and procedures enacted by questionably qualified board members. The Superintendent of schools tries to advise and influence the board but they make the rules as they wish or as ridiculous they may be such as 2 week leave upon exposure. No teacher protections and a forced 2-week unpaid leave if one of their students get sick. I'm not sure if the students are even required to mask except on the bus. Even if they are it would be a nightmare to try and enforce. They do temperature scan students FWIW on entry to the building. I'm not going to get into unions and have been on both sides of that fence at one time or another except to say I did better without them...
 

nsaspook

Joined Aug 27, 2009
16,328
I wonder why many people are afraid of getting a vaccine shot?
I am not afraid of a Pfizer or Moderna vaccine but I am wary of a new vaccine made by a new company that has never made or tested a vaccine before.
Movies, popular media and the typical fear of the unknown maybe.

The bad side-effects I've seen are mainly incidental illness caused, not a direct result of the shot.

Enormous resources have been used to create the current vaccines and test safety. Some are giving up.
https://www.statnews.com/2021/01/25...two-covid-19-vaccines-and-focus-on-therapies/
 

justtrying

Joined Mar 9, 2011
439
How about using this wonderful new technology to develop vaccines for malaria, aids and tuberculosis? Imagine how many people that would save? Except you would not need to take them every year :(

And HIV is controlled by taking drugs for life. Now that is a good treatment.

Long term safety of mRNA vaccines will be known eventually.
 

SamR

Joined Mar 19, 2019
5,491
There has already been a lot of questioning about the efficacy and safety of the chinese vax being administered mostly in Africa. I don't get it but there is a lot of pushback from the antivaxers and tons of ridiculous misinformation being disseminated. Maybe they actually believe the propaganda out of Iran about the US vax. True freedom does require some compliance to norms and acting responsibly.
 

nsaspook

Joined Aug 27, 2009
16,328
There has already been a lot of questioning about the efficacy and safety of the chinese vax being administered mostly in Africa. I don't get it but there is a lot of pushback from the antivaxers and tons of ridiculous misinformation being disseminated. Maybe they actually believe the propaganda out of Iran about the US vax. True freedom does require some compliance to norms and acting responsibly.
There should be questions with a inactivated coronavirus vaccine. That said I'm pretty sure the military give me shots half a century ago that were much worse and far less tested.
https://www.bbc.com/news/world-latin-america-55642648
A coronavirus vaccine developed by China's Sinovac has been found to be 50.4% effective in Brazilian clinical trials, according to the latest results released by researchers.
It shows the vaccine is significantly less effective than previous data suggested - barely over the 50% needed for regulatory approval.
The Chinese vaccine is one of two that the Brazilian government has lined up.
 

justtrying

Joined Mar 9, 2011
439
It would still be blue as you see it, because the illusion of color happens in the mind, not the eyes.

When I see how some people dress or paint their homes, I often wonder if we all perceive color the same.
Sorry to continue off topic, but cones in your retina are sensors. They differ in sensitivity between people. Brain processes the input, that is true, but ths input is not the same for everyone because the sensors are not "calibrated" to the same standard, some are more sensitove than others
 

wayneh

Joined Sep 9, 2010
18,105
I wonder why many people are afraid of getting a vaccine shot?
I believe ignorance is at the top of the list. That and a human tendency to be very vulnerable to anecdotes and rumors of bad news, and less swayed by statistics.

Among thinking people, there is room for legitimate concern about some unknown long-run problem. I don't think there's any precedent for that in vaccines, but a Black Swan could still be lurking out there. In the meanwhile there's plenty of data showing minimal short term risk and a clear benefit. If we had to pay a lot to get it, things might be different. Of course we've already paid for the darn thing.
 

justtrying

Joined Mar 9, 2011
439
I believe ignorance is at the top of the list. That and a human tendency to be very vulnerable to anecdotes and rumors of bad news, and less swayed by statistics.

Among thinking people, there is room for legitimate concern about some unknown long-run problem. I don't think there's any precedent for that in vaccines, but a Black Swan could still be lurking out there. In the meanwhile there's plenty of data showing minimal short term risk and a clear benefit. If we had to pay a lot to get it, things might be different. Of course we've already paid for the darn thing.
Well, if you are healthy and under 60, what is the PROVEN benefit of getting it? We already know the risks of this particular disease are very low to that age group.

The media is making it worse. A 19 year old who died of overdose was reported as having died of COVID.

The PHO in BC keeps telling people every day that they must do more to stop the spread. What more can they do? The outbreaks are all in long term care. Majority is doing all they can.
 

SamR

Joined Mar 19, 2019
5,491
And some of us are genetically lacking and monochromat... No, I don't see in shades of gray and I can determine green and red IF there is sufficient area, hue, saturation, and not pastel. I can't see those little red berries on the side of the road my wife points out but I can pass the color exam for my driver's license. My grandfather however could not even though I inherited the deficiency from him. Out of his 7 grandsons, only 2 of us are colorblind. The area of Psychology dealing with sensation is very interesting and our senses are prone to misinterpretation. Touch seems to be the most reliable but even it can have trouble discerning between hot and cold.
 

wayneh

Joined Sep 9, 2010
18,105
Well, if you are healthy and under 60, what is the PROVEN benefit of getting it? We already know the risks of this particular disease are very low to that age group.
Yeah, I avoided that detail. It still reduces the odds of ending up in the hospital, but from an already low level. Although for certain people the risk is much higher. It'd be great if we could identify those folks. On average, people with adequate vitamin D levels and no co-morbidity have little to fear.

The younger and healthier you are, the less incentive there is at a personal level. It may help society as a whole, but since when do twenty-somethings care about that?
 

justtrying

Joined Mar 9, 2011
439
And some of us are genetically lacking and monochromat... No, I don't see in shades of gray and I can determine green and red IF there is sufficient area, hue, saturation, and not pastel. I can't see those little red berries on the side of the road my wife points out but I can pass the color exam for my driver's license. My grandfather however could not even though I inherited the deficiency from him. Out of his 7 grandsons, only 2 of us are colorblind. The area of Psychology dealing with sensation is very interesting and our senses are prone to misinterpretation. Touch seems to be the most reliable but even it can have trouble discerning between hot and cold.
My neighbor is colorblind. When he first bough his house it was red. He said he really dislikes red. It was interesting to me.
 

Deleted member 115935

Joined Dec 31, 1969
0
Well, if you are healthy and under 60, what is the PROVEN benefit of getting it? We already know the risks of this particular disease are very low to that age group.

The media is making it worse. A 19 year old who died of overdose was reported as having died of COVID.

The PHO in BC keeps telling people every day that they must do more to stop the spread. What more can they do? The outbreaks are all in long term care. Majority is doing all they can.

In UK, most sick elderly are in care homes,
most deaths are in the sick elderly, QED, care home deaths are high
Not helped by the difficulties in distancing in that environment.

It seems most carriers are now in the middle age group.

The proven benefit of having an inoculation is the lower probability of catching CV19, and lower effects if you do get it.
Now you could argue that statistics are not proof, I get that, but what proof would one accept if not statistics ?

You say about the sad death of someone from an overdose, which was counted as a CV19 death.
A few ways to look at that I think,
Having CV19 is liable to push anyone over the edge who is feeling depressed.
Even just the "lockdown" seems to be corelated to an increase in suicides and depression.
Now does that mean we should not lock down ?

Now one could argue that the lockdown causes more deaths due to un employment, long term stress etc.

I would say, and it needs lots more numbers I would say to prove it, that the lockdown deaths are lower than the CV19 deaths would be. so on balance as we can not prove, we have to best guess, lockdown is the "better" option,

As for risk to the younger age group ,
The long term CV19 effects are just as strong in the younger age group as the older groups as far as i know,

the long term effects are terrible for a good few people.

End of the day
Id prefer not to get CV19,
I'd not want to be a spreader,

So Im getting a jab asap.
 

justtrying

Joined Mar 9, 2011
439
In UK, most sick elderly are in care homes,
most deaths are in the sick elderly, QED, care home deaths are high
Not helped by the difficulties in distancing in that environment.

It seems most carriers are now in the middle age group.

The proven benefit of having an inoculation is the lower probability of catching CV19, and lower effects if you do get it.
Now you could argue that statistics are not proof, I get that, but what proof would one accept if not statistics ?

You say about the sad death of someone from an overdose, which was counted as a CV19 death.
A few ways to look at that I think,
Having CV19 is liable to push anyone over the edge who is feeling depressed.
Even just the "lockdown" seems to be corelated to an increase in suicides and depression.
Now does that mean we should not lock down ?

Now one could argue that the lockdown causes more deaths due to un employment, long term stress etc.

I would say, and it needs lots more numbers I would say to prove it, that the lockdown deaths are lower than the CV19 deaths would be. so on balance as we can not prove, we have to best guess, lockdown is the "better" option,

As for risk to the younger age group ,
The long term CV19 effects are just as strong in the younger age group as the older groups as far as i know,

the long term effects are terrible for a good few people.

End of the day
Id prefer not to get CV19,
I'd not want to be a spreader,

So Im getting a jab asap.
Just remember, it is not known to what level (if any) vaccine prevents transmission so act accordingly.

What is happening with "statistics" is everyone who dies is tested for COVID. In years prior, was everyone who died of an overdose or a heart attack swabbed for flu?

Statistics could be made to show anything you want. Same statistics can be interpreted in a completely different way.

No one wants to get sick. Not trying to minimize anything. The thing is seemingly healthy people also die every day. Aneurisms, blood clots, undiagnosed conditions etc etc.

I always thought that life is for living.
 

SamR

Joined Mar 19, 2019
5,491
really dislikes red. It was interesting to me.
To those completely lacking in red receptors, it appears a blah muddy brown. Not a popular color. Interestingly, since I am red and green deficient, I like blue. My wife is an artist and has acute color vision. When we built our house she drove the contractor nuts. She had each room of the house painted a different tint of the same color and he couldn't tell the difference between them and got some of the cans mixed up much to her displeasure and his consternation.
 

nsaspook

Joined Aug 27, 2009
16,328
Just remember, it is not known to what level (if any) vaccine prevents transmission so act accordingly.

What is happening with "statistics" is everyone who dies is tested for COVID. In years prior, was everyone who died of an overdose or a heart attack swabbed for flu?

Statistics could be made to show anything you want. Same statistics can be interpreted in a completely different way.

No one wants to get sick. Not trying to minimize anything. The thing is seemingly healthy people also die every day. Aneurisms, blood clots, undiagnosed conditions etc etc.

I always thought that life is for living.
Can we put you down as undecided?
 

Deleted member 115935

Joined Dec 31, 1969
0
Re the death rate,
In the UK , they started out as recording every one who dies who had ever had cv19 as being a cv19 death.
They soon changed that to (a) if you have CV19 on the death register or (b) within 28 days of having CV19

I'm assuming the reason for reporting, is to try to plan response.. I use the word plan loosely in the UK...

I guess its a compromise between over reporting and under reporting and speed of reporting.

great data to late is useless to plan with,
terrible data is useless to plan with even if its quick

So the powers that be have taken a good guess,

At the end of the day
if its 2M or 2.2 or 1.8 M that have died of covid so far

I still think its a terrible burden and is almost un imaginable in this day and age.

may they rest in peace,
 
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