https://spectator.org/a-report-from-the-front/

That is a great article, and it supports what I have said all along, "the President's commission lacks clinical representation/diversity." That is, clinicians who are on the front lines, not in laboratories doing HIV research. In a now deleted response, I also pointed out that our natural immune response can do more damage than good. By analogy, we respond to cordon off the invader and kill it. That response leads to scaring, and sometimes the resultant scaring is even worse. An example is a child with sever burns to the face and upper body. We can almost always save that child's life, but it is far more difficult to prevent the scaring.

In the area of infectious diseases, the Schwarzman reaction (https://en.wikipedia.org/wiki/Shwartzman_phenomenon) is a classic example where our natural response actually does harm. Of course, viruses do not produce endotoxin, but that is just an example. One of my daughters is a lead nurse in a "regenerative medicine" lab in the Midwest. Early on, she told me their research was directed not at clearing the SARS-CoV-2 virus, but in preventing our body's self-destructive response to it.

I am glad to see others see the same thing. I hope the President's Commission will include those viewpoints.

 

That is a great article, and it supports what I have said all along, "the President's commission lacks clinical representation/diversity." That is, clinicians who are on the front lines, not in laboratories doing HIV research. In a now deleted response, I also pointed out that our natural immune response can do more damage than good. By analogy, we respond to cordon off the invader and kill it. That response leads to scaring, and sometimes the resultant scaring is even worse. An example is a child with sever burns to the face and upper body. We can almost always save that child's life, but it is far more difficult to prevent the scaring.

In the area of infectious diseases, the Schwarzman reaction (https://en.wikipedia.org/wiki/Shwartzman_phenomenon) is a classic example where our natural response actually does harm. Of course, viruses do not produce endotoxin, but that is just an example. One of my daughters is a lead nurse in a "regenerative medicine" lab in the Midwest. Early on, she told me their research was directed not at clearing the SARS-CoV-2 virus, but in preventing our body's self-destructive response to it.

I am glad to see others see the same thing. I hope the President's Commission will include those viewpoints.

https://www.the-scientist.com/news-...unaway-immune-responses-treat-covid-19--67450

Regarding ventilation - system moves slowly... I have read about changes in recommended protocol and disease progression/presentation (how it is nothing like typical ARDS) and ventilation outcomes (very poor) probably a month ago. Our health authority has not shifted on their recommendations.

 

https://www.the-scientist.com/news-...unaway-immune-responses-treat-covid-19--67450

Regarding ventilation - system moves slowly... I have read about changes in recommended protocol and disease progression/presentation (how it is nothing like typical ARDS) and ventilation outcomes (very poor) probably a month ago. Our health authority has not shifted on their recommendations.

So? Contact your "health authority." Is that person a practicing clinical physician seeing COVID-19 patients in the ICU? If not, why not?

 

So? Contact your "health authority." Is that person a practicing clinical physician seeing COVID-19 patients in the ICU? If not, why not?

Practicing physicians are bound by protocols handed down to them. I believe there were comments made at some point about protocols and their value at a previous thread.

Only physicians and "working groups" can change those protocols.

I, being in charge of medical equipment, do not even have enough power to enforce basic safety protocols that physicians and other medical personelle are supposed to be following in order to avoid patient harm. This is why equipment has so many alarms now, in turn causing alarm fatigue and complacency and further issues. It is a ficious cycle.

We are obviously in the opposite corners here regarding medical field.

FYI, i do what I can to provide information to people I work with. You can easily guess where this information goes to die

 

Practicing physicians are bound by protocols handed down to them. I believe there were comments made at some point about protocols and their value at a previous thread.

Only physicians and "working groups" can change those protocols.

NOT in the United States. A physician can have the last say if he/she is competent enough to take that chance.

I, being in charge of medical equipment, do not even have enough power to enforce basic safety protocols that physicians and other medical personelle are supposed to be following in order to avoid patient harm. This is why equipment has so many alarms now, in turn causing alarm fatigue and complacency and further issues. It is a ficious cycle.
We are obviously in the opposite corners here regarding medical field.

FYI, i do what I can to provide information to people I work with. You can easily guess where this information goes to die.

"You can easily guess where this information goes to die." Been there. Stick with what you know is right.

I agree. I have seen a lab cited for an "egregious error" ( That characterization has a major legal consequence in the US.) for disabling a defective "bubble" warning that was not even required for license of the equipment by our FDA. The logical consequence was not to do platelet transfusions or ignore the meaningless warning. Our FDA inspector felt we should have done the former. I ended up in a Federal Court house in Philadelphia with two top executives from our medical center and a room full of FDA attorneys explaining my preference to treat patients. There was no further adverse action at that time. The FDA inspector was, of course, primed for her next visit.

 

I found this article rather interesting. It's on why comparing CV-19 to influenza is the wrong approach:

https://edition.cnn.com/2020/05/01/health/flu-vs-coronavirus-deaths/index.html

​

 

"Death by Coronavirus"

I found this article rather interesting. It's on why comparing CV-19 to influenza is the wrong approach:

https://edition.cnn.com/2020/05/01/health/flu-vs-coronavirus-deaths/index.html

View attachment 205939​

The only less bad news is that it's also possible the CV pandemic will burn humanity at a faster rate and be over sooner that a typical influenza pandemic.

Peak death now, Peak death later or slow death for a while?

https://www.statnews.com/2020/05/01/three-potential-futures-for-covid-19/

In one future, a monster wave hit in early 2020 (the current outbreak of millions of cases and a projected hundreds of thousands of deaths globally by August 1), but is followed by alternating mini-waves of much smaller outbreaks every few months with only a few (but never zero) cases in between.

In the second scenario, the current monster wave is followed later this year by one twice as fierce and even longer-lasting, as the outbreak rebounds after a summer when a significant drop in the number of cases and deaths led officials and individuals to let down their guard, relax physical distancing more than was safe, and fail to heed (or even detect) the early warning signs that a new outbreak was gathering force. After this doubly disastrous second wave, the sea is almost calm, marred only by an occasional wave of cases that number barely one-fifth of what the fall and spring of 2020 saw.

In the third possible future, the current wave creates a new normal, with Covid-19 outbreaks of nearly equal size and, in most cases, duration through the end of 2022. At that point, the best-case scenario is that an effective vaccine has arrived; if not, then the world experiences Covid-19 until at least half of the population has been infected, with or without becoming ill.

 

 

Good news!
https://thehill.com/changing-americ...no-evidence-of-coronavirus-reinfections-south

Researchers in South Korea say reports of recovered coronavirus patients testing positive for COVID-19 for a second time are due to testing errors and not reinfection.

South Korea’s infectious disease experts said Thursday that dead virus fragments picked up by COVID-19 tests likely caused more than 260 people in the country to test positive again for the coronavirus, days, and sometimes weeks, after making full recoveries, according to The Korea Herald.

 

Good news!
https://thehill.com/changing-americ...no-evidence-of-coronavirus-reinfections-south

That's great news indeed...

 

Looks like I picked the wrong week to quit smoking.


https://www.qeios.com/read/FXGQSB.2

SARS-CoV-2 epidemics raises a considerable issue of public health at the planetary scale. There is a pressing urgency to find treatments based upon currently available scientific knowledge. Therefore, we tentatively propose a hypothesis which hopefully might ultimately help saving lives. Based on the current scientific literature and on new epidemiological data which reveal that current smoking status appears to be a protective factor against the infection by SARS-CoV-2 [1], we hypothesize that the nicotinic acetylcholine receptor (nAChR) plays a key role in the pathophysiology of Covid-19 infection and might represent a target for the prevention and control of Covid-19 infection.

https://www.medrxiv.org/content/10.1101/2020.04.08.20057794v1.full.pdf
Factors associated with hospitalization and critical illness among 4,103 patients with Covid-19 disease in New York City

Surprisingly, though some have speculated that high rates of smoking in China explained
some of the morbidity in those patients, we did not find smoking status to be associated with
increased risk of hospitalization or critical illness. This is consistent with a handful of other
studies that have previously shown a lack of association of smoking with pulmonary diseaseassociated ARDS (i.e. from pneumonia), as compared with non-pulmonary sepsis-associated
ARDS.

 

Looks like I picked the wrong week to quit smoking.
View attachment 205980

https://www.qeios.com/read/FXGQSB.2


https://www.medrxiv.org/content/10.1101/2020.04.08.20057794v1.full.pdf
Factors associated with hospitalization and critical illness among 4,103 patients with Covid-19 disease in New York City

Really old news.

 

Really old news.

Missed it or forgot about it.

 

Utopia == Hell.

Funny on soooo many levels.

 

 

Utopia == Hell.

Funny on soooo many levels.

Living the life their parents did at Woodstock.

 

My state, Massachusetts, has the third highest number of cases. The per capita cases are worse. Unfortunately, we are FIRST. NY has 62 cases per 1000 residents. MA has 106 cases per capital. That’s over 10% of Massachusetts residents.

I created the table that shows for each of the top three states: population, coronavirus cases and cases per 1000 residents.

Per Capita
NY
19.45 M 314KCV 62
NJ
8.82 M 121K CV 73
MA
6.81 M 64K CV 106

 

My state, Massachusetts, has the third highest number of cases. The per capita cases are worse. Unfortunately, we are FIRST. NY has 62 cases per 1000 residents. MA has 106 cases per capital. That’s over 10% of Massachusetts residents.

I created the table that shows for each of the top three states: population, coronavirus cases and cases per 1000 residents.

Per Capita
NY
19.45 M 314KCV 62
NJ
8.82 M 121K CV 73
MA
6.81 M 64K CV 106

Maybe the Mandatory Mask Order will fix that.
https://www.nbcboston.com/news/local/what-to-know-about-massachusetts-mandatory-mask-order/2117445/

More than half the state’s deaths have been people in long-term-care facilities, such as nursing homes. The elderly make up a slightly higher share of the Massachusetts population than the national average.

IMO the primary root failure has been and continues to be the inability to isolate and protect the frail and elderly from the very beginning. Unfortunately masks and social distancing in the general population is unlikely actually stop the spread to the frail and elderly because of frail and elderly spreaders already in long-term-care facilities.

 

My state, Massachusetts, has the third highest number of cases. The per capita cases are worse. Unfortunately, we are FIRST. NY has 62 cases per 1000 residents. MA has 106 cases per capital. That’s over 10% of Massachusetts residents.

I created the table that shows for each of the top three states: population, coronavirus cases and cases per 1000 residents.

Per Capita
NY
19.45 M 314KCV 62
NJ
8.82 M 121K CV 73
MA
6.81 M 64K CV 106

10%? I think it is closer to 1% (0.94%). That is, 64x10^3/6810x10^3 .

 

10%? I think it is closer to 1% (0.94%). That is, 64x10^3/6810x10^3 .

Damn decimal point keeps moving.