Your question has z.e.r.o. useful information. It is worse than your question in the other thread. In that thread you have not responded to any of the feedback you received.
For example, if the signal is the 50,000 W output of a TV transmitter, "conditioning" it is difficult.
What type of "conditioning"? Filtering? Transient suppression? Common mode noise rejection? Gain? Attenuation? Inversion?
This is not a free homework service. Show us your design, and we will advise.