Coronavirus?!

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xox

Joined Sep 8, 2017
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who is she blackmailing? Is she blackmailing those people between current and 70% (so everyone can get released from constraints), or is she blackmailing those last 30% of people who refuse to get vaccinated by allowing all other non-vaccinated people to spittle on each other as they scream in the arena?
Until she gets her way, 100% of the entire state. Oregon is showing something like 3 deaths per day right now. Covid is about as "under control" as it's going to get.

None of this is very surprising of course. This is the same person that defended the riots which have caused incalculable damage to the state. Disgusting!
 

MrSalts

Joined Apr 2, 2020
2,767
Until she gets her way, 100% of the entire state. Oregon is showing something like 3 deaths per day right now. Covid is about as "under control" as it's going to get.

None of this is very surprising of course. This is the same person that defended the riots that have caused incalculable damage to the state. Disgusting!
Zero new infections and zero deaths is a as under control as it's going to get. Set your goals high and see how easily quality outcomes can be achieved. Zero was possible way before a vaccine. The problem was that people couldn't follow rules and there was a shortage of PPE for the people in certain occupations. Note, there isn't a PPE shortage today so why is anyone getting infected - why are there ANY deaths? Two weeks of completely following rules & quarantine would be all it should take.
 

xox

Joined Sep 8, 2017
936
Zero new infections and zero deaths is a as under control as it's going to get. Set your goals high and see how easily quality outcomes can be achieved. Zero was possible way before a vaccine. The problem was that people couldn't follow rules and there was a shortage of PPE for the people in certain occupations. Note, there isn't a PPE shortage today so why is anyone getting infected - why are there ANY deaths? Two weeks of completely following rules & quarantine would be all it should take.
Sure, that isn't at all UNREASONABLE. Why don't we just extend that to all viruses while we're at it? Lockdowns forever everyone!
 

MrSalts

Joined Apr 2, 2020
2,767
Sure, that isn't at all UNREASONABLE. Why don't we just extend that to all viruses while we're at it? Lockdowns forever everyone!
Or just follow the rules - I don't think Portland is locked down. Or do you define mask-wearing as a lockdown?
 

killivolt

Joined Jan 10, 2010
836
BTW, everyone who has read the book, say don't bother watching the Oprah film version on Crave. It's all about her daughter. :(
I did broadcast for my University and while covering a class I learned of her, just had to get the book they spoke of definitely interesting story.

Apparently
The doctor who first cultivated Lacks' cells, Dr. George Gey, originally shared them with colleagues for free. Several years later, a factory was set up to mass-produce the HeLa (Henrietta Lacks) cells at a rate of about 6 trillion cells a week
There's no way of knowing exactly how many of Henrietta's cells are alive today. One scientist estimates that if you could pile all HeLa cells ever grown onto a scale, they'd weigh more than 50 million metric tons
Amazing
kv
 

MrSalts

Joined Apr 2, 2020
2,767
Unfortunately it was done without her knowledge and consent.
A lot of things are done without knowledge and consent. Were her cells unique, yes (everybody's cells are equally unique). We're her cells irreplaceable? No, before the first experiment, anybody's cells could have been used. Research is done daily on donated blood, donated cadavers, recovered placentas and spit samples used for DNA testing. Even the little piece of skin from a circumcision is cultured, extended, and used to make a skin graft matrix. All of these examples are done without specific consent. If consent is actually given, it is usually in the fine print of the admission papers you sign when entering the hospital.

The 1990 US Supreme Court decided that tissues removed from a body were no longer owned by the patient and would have been discarded so they have no value to the patient and the patient cannot sue for the eventual value the tissue acquires because of processing or marketing effort by others.
Also, it is considered immoral for a patient to sell their own organs or for family members to sell them (whether the donor is living or dead).
 

MaxHeadRoom

Joined Jul 18, 2013
30,663
We're her cells irreplaceable? No, before the first experiment, anybody's cells could have been used.
So everybody's cells are immortal? i.e. re-create, if so why not discovered before and others used since in place of hers?
And several companies making money from these particular ones?

HeLa cells have anywhere from 76 to 80 total chromosomes, which is different from other normal cells (total 46 chromosomes). ...
The telomerase, which allows for addition of sequences at the end of chromosomes, is active during the process of HeLa cell division. So DNA will not be damaged and the cell does not die
 
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MrSalts

Joined Apr 2, 2020
2,767
So everybody's cells are immortal? i.e. re-create, if so why not discovered before and others used since in place of hers?
And several companies making money from these particular ones?

HeLa cells have anywhere from 76 to 80 total chromosomes, which is different from other normal cells (total 46 chromosomes). ...
The telomerase, which allows for addition of sequences at the end of chromosomes, is active during the process of HeLa cell division. So DNA will not be damaged and the cell does not die
there are many cell lines in the marketplace that are "immortal". The term is used because there are so many samples and all viable. "Her" cells were cervical cancer cells - not her standard human cells. If an organism has an inconsistent number of chromosomes, it is a blended or grafted species and definitely not human at 76 to 80 chromosomes. One additional chromosome causes issues like Downs Syndrome, or any of the various other trisomy syndrome. Extra Y chromosomes (the smallest chromosome) are less bothersome but can cause developmental or issues with excessive Testosterone.

Like any highly replicated DNA or RNA sequences, replication errors occur (mutations). HeNe cells are not immune to replication errors. The HeNe cell line is interesting and a model for testing various therapeutic agents because there are many human genes present, but the value as a human model has depreciated with each generation of mutations.

The initial value of the HeNe sell line was that it was a common base to test drugs across labs and researchers and experiments. It didn't matter who the line was - it mattered that there was an experimental standard. Experimental standards were always available in electrical engineering but new to Biology/Medicine in the 1950s.

Here is an interesting but from BioMedical Central
While interesting, debates such as this seem to miss one fundamental scientific issue. The present HeLa genome, or any other HeLa genomes, while derived from Henrietta Lacks’s genome is not her personal genome. There is no doubt that the majority of DNA sequences are identical between HeLa cells and Lacks’ original cells.

However, HeLa cell genome and Lacks’s genome show very little similarity. Lacks’ genome originally contained 46 normal chromosomes while most HeLa cells have 70-90 chromosomes with over 20 translocations, some of which are highly complex involving multiple chromosomal rearrangements.

To fully appreciate this point, one has to understand and define what the genome is. The genome is not just a collection of genes, arranged like pearls in a string. While individual genes produce functional parts or proteins, the genome structure has a function defined by the karyotype that provides the blueprint that describes how these parts work together (4-5).

In other words, the genome defines the network structure by providing the “system inheritance”. It is the karyotype rather than DNA sequence that defines the identity of the cell line as different derived cell lines could have similar sequences but different karyotypes (or genome context). This concept has recently been illustrated by re-interpretation the main function of sex, and the importance of the karyotype.

It turns out, karyotype rather than specific genes define the identity of the species (6-8). In the case of the HeLa genome, the changes generated over the past few decades have occurred through multiple runs of genome re-organization during cancer evolution and initial cell culture experimentations.

These changes not only differ greatly from Lacks’s original genome but it can be argued that the HeLa genome is not actually a human genome anymore. In fact, some evolutionary biologists consider cancer cell such as HeLa cells to be their own unique species (see works of Julian Huxley and Leigh Van Valen).

In recent years, an increase of investigators including our own group have proposed/supported the notion that many cancer cells are no longer “human cells,” as judged by karyotypic changes (for more information, please check out our references on genome theory) (9-12).
Again, humans have 46 (twenty three pairs) of chromosomes.
https://blogs.biomedcentral.com/on-...-line-identity-and-the-privacy-of-patients-2/
 
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