Coronavirus?!

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SamR

Joined Mar 19, 2019
5,491
This is simply a clinical trial of an already manufactured "viral" treatment drug to test its efficacy against the "chinese death flu". Not a prevention drug but merely a drug that may benefit treatment after becoming infected. There is an anti-infection vaccine ready for testing but like the SARS the anti-infection vaccine will too little too late after testing and approval by the FDA.
 

dl324

Joined Mar 30, 2015
18,329
The rest of the world should do what Iran is doing. They say they'll have their outbreak under control within 3 weeks according to a quote in this AP article.

That's weeks before the US will have it under control due to warmer weather in April (fake news).
 

SamR

Joined Mar 19, 2019
5,491
Yeah that's the ticket!!! Just lie and it will go away!

Iran's Cyber Police reported that 24 people were arrested and 118 other were warned about “spreading rumors" on the internet about the virus.

“Coronavirus must not be turned into a weapon for our enemies to halt work and production in our country,” Rouhani said.
 

dl324

Joined Mar 30, 2015
18,329
I think it might be Iran removing the overhead handles in their subway system to reduce the places where the virus might come in to contact with people...o_O

They're saying the US is lying about deaths and referencing the number of deaths from seasonal flu.
 

jpanhalt

Joined Jan 18, 2008
11,087
Participants will receive 200 milligrams of remdesivir intravenously when they're enrolled and another 100 while they're hospitalized for up to 10 days in total. A placebo group will receive a solution that resembles remdesivir but contains only inactive ingredients, the NIH said.
Generally, one uses the best current medication in the control group. Chloroquine has been mentioned and is oral. Surely if that is being used, it would continue to be used at least in the control patients. In fact, one could argue that since chloroquine works very differently, if it is being used as the "best available" treatment, it should continue to be used in both groups. That might make blinding more difficult, but good study design is not worth denying a patient the best available treatment if mortality is the other option.
 

dl324

Joined Mar 30, 2015
18,329
That might make blinding more difficult, but good study design is not worth denying a patient the best available treatment if mortality is the other option.
I was just thinking about that. What kind of ethics decision would medical people be making if they were denying treatment to someone who could die from the illness for the sake of the greater good? I guess people who signed up for the trials would have to acknowledge that they knew, and accepted, the risks. But still...
 
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SamR

Joined Mar 19, 2019
5,491
I think it might be Iran removing the overhead handles in their subway system to reduce the places where the virus might come in to contact with people...o_O
I guess they don't have any gloves to go along with the masks?!?! Wait a minute! They can start cutting hands off! Yeah that will work!
 

jpanhalt

Joined Jan 18, 2008
11,087
I guess people who signed up for the trials would have to acknowledge that they knew, and accepted, the risks. But still...
An almost absolute requirement for participation in a medical study is "informed consent." That presents problems. For example insane people, unconscious people, children, prisoners, and in this instance,, people who may have an irrational fear of dying from their disease. Given our 100% survival rate so far, I think ethically, it should be impossible to deny every participant the best current alternative.

Consider that drugs for headache , pain, and so forth are highly affected by perception. There are no hard and fast criteria. Drugs for infection, diabetes, and so forth present a different scenario. There are good definitions for endpoint. Hence, clinical studies for antibiotics may include the current most effective therapy until some efficacy is shown. (In the US, clinical trials are divided into phases (https://www.fda.gov/patients/drug-development-process/step-3-clinical-research ). I suspect phase 1 has been completed for the antiviral drug being tested. Efficacy (phase 2) has not been completed for this etiologic agent.
 

killivolt

Joined Jan 10, 2010
836
We are a Society of non believers, it’s not until it’s in our face literally will we acknowledge. I’m surprised by the factual and non factual, but I get it, nothing lost there. However, if we have a contamination or pandemic, we should be a little more aware of those around us, show more love and affection, take advantage because we are not able to see the future, I’m sure in history we have found that many people without current health care caught by things beyond our capability to control, didn’t take time to appreciate because of environment of employment or other issues etc.

We have controlled things for so long we forgot that this virus is a living creature looking for a host. Viruses like the Spanish Flu found residency in many hosts, after it had successfully mutated to move from host to host until it lost people who then became immune . Thus, we no longer have hosts for the Virus to continue to infect.

Afterword, the virus lost and people won to continue on in time, spend time as much as you can and remember the most important things are what matters.

This is certainly not doomsday post, but it is a reality check for all of us no matter what the degree of issues we face today.

This is my shout out to my AAC members, remember that little things matter most.

kv
 

Berzerker

Joined Jul 29, 2018
624
dl324 said:
The rest of the world should do what Iran is doing. They say they'll have their outbreak under control within 3 weeks according to a quote in this AP
SamR said:
Wait a minute! They can start cutting hands off! Yeah that will work!
I think they would aim a little higher, like the head. Best way "NOT" to spread the virus is to have no people "WITH" the virus. Brutal but effective. Burn the bodies and claim "We got it under control". 3 weeks seems a little long to kill (X) amount of people. We now have learnt that some how the virus got out of the quarantined area and infected a non traveling person and they're in critical condition. It's been reported that the people sent there to help might have accidently let it out.
 

Berzerker

Joined Jul 29, 2018
624
You didn't post a link to them so I went looking them up. These things are a best seller! $23-$27 according to where you go. Not sure how others would take it if you wore something like this in public though.
 

nsaspook

Joined Aug 27, 2009
16,326
https://www.oregonlive.com/news/2020/02/coronavirus-appears-in-oregon.html
A Lake Oswego elementary school employee contracted Oregon’s first apparent case of coronavirus, causing the closure of the 430-student school as health officials try to figure out how many people may have been exposed.

The employee lives in Washington County and is isolated at Kaiser Permanent Westside Medical Center in Hillsboro in what state health officials described Friday as another case of an unexplained transmission of the disease.

The patient hadn’t been under monitoring for coronavirus symptoms and doesn’t appear to have traveled to any of the countries with outbreaks of the disease or have associated with anyone who did, Oregon Health Authority officials said.

That means the person could have caught the disease from someone in the community.
 

nsaspook

Joined Aug 27, 2009
16,326
https://www.prnewswire.com/news-rel...ericans-wouldnt-buy-corona-now-301012225.html
5WPR's survey found that:

  • 38% of beer-drinking Americans would not buy Corona under any circumstances now
  • Among those who said they usually drink Corona, only 4% said they would stop drinking Corona, but 14% said they wouldn't order Corona in a public venue
  • 16% of beer drinking Americans were confused about whether Corona beer is related to the coronavirus
o_O

(link to inappropriate video removed by a moderator. Please read the 11th line of the Terms Of Service https://forum.allaboutcircuits.com/help/terms/)
 
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