We have been using these guys are work lately and are quite happy with them.. https://www.mclpcb.com/
We get the boards from their China location but always just deal with the local guys in the US
They have gone above and beyond on many occasions..
HW electronics
Seeed/Fusion
allpcb
several others i can't remember.
most don't have panel/v-score capability.
some with good quality try to rob you on shipping.
some demand TT payment which costs $50 just to process. i prefer paypal, quick and easy.
i prefer china direct, the US suppliers just buy them from china and mark em up.
i used to have a good US maker but they closed shop.
What do you mean by "high volume" - 1000, 5000, 50 thousand?
[EDIT] - any board house without V-groove scoring capability is Mickey Mouse by today's standards (actually by the standards of at least a decade ago), however metal core is outside of the ability of some good manufacturers.
I haven't had boards fabbed for quite some time, buy I was always satisfied with Advanced Circuits. I don't know if they do metal core. Here is their capabilities page.