Mutant Plastic Enzyme

wayneh

Joined Sep 9, 2010
18,104
https://www.theguardian.com/environ...reate-mutant-enzyme-that-eats-plastic-bottles

"The new research was spurred by the discovery in 2016 of the first bacterium that had naturally evolved to eat plastic, at a waste dump in Japan. Scientists have now revealed the detailed structure of the crucial enzyme produced by the bug."

No problem plastic.
More sensationalist journalism. The mutation gave a 20% boost in...something they didn’t bother to define (could be rate, lifetime, or an artifact within experimental error). It’s interesting, but the headline makes it sound like a lot more.
 

profbuxton

Joined Feb 21, 2014
421
Wow, imagine if this was factual. would all plastic be under threat if this "bug" got loose. Can you imagine how it would affect our world if plastics were "eaten" by a "bug".
 

wayneh

Joined Sep 9, 2010
18,104
Wow, imagine if this was factual. would all plastic be under threat if this "bug" got loose. Can you imagine how it would affect our world if plastics were "eaten" by a "bug".
I wouldn't worry too much. Enzyme reactions (and thus life) require surface area and water, and usually other things such as cofactors. For many or most plastic applications, the plastic has a low surface-area-to-volume ratio (ie. is not shredded) and is not in contact with water.
 

Thread Starter

BR-549

Joined Sep 22, 2013
4,931
Wouldn't that be something. Instead of a human pandemic....a fossil fuel, plastic pandemic.

Make a good novel. How devastating would it be?

Without our disposable plastics.......I don't believe our heath care could function. Not to mention trade.
 

profbuxton

Joined Feb 21, 2014
421
There were two novels in this vain written many years ago. Don't recall the author as I didn't read them. Titles were "The death of steel" and "The death of grass". I believe the premise was some sort of "bug" causing steel and grass to die.
Must see if i can dig them up somewhere.
 

wayneh

Joined Sep 9, 2010
18,104
I can't get past the suspension of disbelief. Solid substrates are very resistant to enzyme attack, and even microbes have a hard time getting into them. If there's a big enough thermodynamic drop to be had, something will come along with the right biochemistry to exploit it. But it might take thousands of generations for a microbe to evolve into that niche. They need something to live on in the meanwhile.
 

jpanhalt

Joined Jan 18, 2008
11,087
I would not be so pessimistic about what those little bugs can do. They can form adherent biofilms to everything, including Teflon. And, they do not need to get into the plastic for their extracellular enzymes to attack it. That is not to say development in that area is at the same stage as fermentation to make alcohol or antibiotics is, but I don't see that the plastic surface per se will be a no go.

Biofilms:
https://www.sciencedirect.com/science/article/pii/0043135494003333
Extracellular enzymes:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC195314/pdf/aem00043-0307.pdf
 

wayneh

Joined Sep 9, 2010
18,104
I would not be so pessimistic about what those little bugs can do. They can form adherent biofilms to everything, including Teflon. And, they do not need to get into the plastic for their extracellular enzymes to attack it. That is not to say development in that area is at the same stage as fermentation to make alcohol or antibiotics is, but I don't see that the plastic surface per se will be a no go.

Biofilms:
https://www.sciencedirect.com/science/article/pii/0043135494003333
Extracellular enzymes:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC195314/pdf/aem00043-0307.pdf
There’s a big difference between shredded plastic in a “compost pile” environment and plastic bottles on the shelf in the grocery store. The pile will eventually make progress in digesting the plastic. There’s nearly zero risk to clean, dry, undamaged plastic.
 
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