Nothing to do with MOSFET. Your boost converter has a big inrush current problem... What fuse are you using...Another issue I am having is that the fuse in the first converter(interleaved boost converter) is always burning/breaking whenever I power it, before applying PWM I have used irfp840, and irfp460, but it keeps on breaking the fuse, I don't know if its the MOSFET, the AC input is 230VAC.
Isolated op-amps use a modulated RF carrier where the modulation frequency is relative to the input volts. They have an input to output gain of 1.Forgive me if I haven't followed all the messages in this thread, but to measure 400VDC I wonder if you could use an op amp pair, one as an oscillator to generate a square wave to switch the other between zero and (a constant fraction) of the 400V. Then isolate with a 1:1 digital audio transformer - for example the MuRata DA100 series and let the processor do the ADC. May not be terribly accurate but could perhaps be calibrated to provide a satisfactory result...
I've used the ISO122 before, but its not a great op-amp withan input offset of 50mVtoo expensive at £20 in 1000up for a consumer switch-mode power supply.Or you could have a look at some isolation amplifiers like the ISO122 or ISO124.
Bertus