While repairing a circuit (contains semiconductor), I amazed that value of resistance (shown by multimeter) is changes while positive and negative probe position interchanged with each other.
the circuit may contain diodes(resistance changes with polarity) or thermistors(resistance changes with temperature).
Not much can be said without knowing about the circuit in detail.
If any semiconductor junction is in the path between the two probes it will introduce asymmetry in the resistance measurement.
It may help in testing diodes and transistors, or at least detecting their presence in a circuit.
Good circuit:
While measuring resistance between pin 1(positive probe) and ground(negative probe) is 465k ohm.
With reversing probe, resistance is 490k ohm.
Faulty circuit:
While measuring resistance between pin 1(positive probe) and ground(negative probe) is 466k ohm.
With reversing probe, resistance is more than 500M ohm (open). I had changed this IC but still it shows 500M ohm at one condition.