Power electronics Firmware Real-time testing and debugging

Hi,
I'm building a power electronics device based on micro-controller and currently testing run-time performance. I'm using serial port to exchange data between the micro-controller and PC

1. I always have missing samples. any suggestions on how to exchange data in Real-Time with PC. [better not to be MCU vendor specific]
2. I need to monitor many variables during run-time, how to configure watch window to keep updating even if the MCU is running?
3. Can I change the address in the watch-variable window during run-time ?
4. what CI/CD tools available for automating embedded real-time application testing?

Thanks in Advance