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Change-Point detection Method Suggestions ..#2

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Seven778

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Seven778

Joined Feb 2, 2026
1
Hello，I've encountered the same problem as you. I also need to find breakpoints in gene coverage. Currently, my method is to smooth the data using TVD and SG, and then use PELT to search for breakpoints. However, this still results in many false positives. Do you have a better approach?I would be extremely grateful for your reply.Have a nice day！

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https://forum.allaboutcircuits.com/...ection-method-suggestions.193113/post-1814019
 
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