This one happened out in the county several years ago, no real casualties......I've seen two and a half accidents. The half is when a tire flow over the short jersey barrier as I was driving to the airport in Frankfurt, Germany in 1998. Since I didn't see the impact, I'll call it a half. The tire was just in my sight for a fraction of a second and then everyone slammed on their brakes. I was about 7 or 8 cars back.
It turns out, the tire landed in someone's front seat and it was a really bad day. We all got to sit in our cars for 2 hours and think about how fast life can be over.
There was a gas station in the middle of a fork in the road. The mens bathroom door faced the main incoming road. There was a customer in one of the stalls taking care of business when a passing semi lost one of the trailers tires. It crashed through the bathroom door and landed in the next stall.
I think the man was in the appropriate place to avoid soiling his britches.