Depends on the type of pilot and what they are doing.Sounds like a differential equation. Do pilots have to study calculus?
For most pilots, the answer is most assuredly NO. Most pilot training syllabi assume very basic math skills -- arithmetic is about it. So things are presented in tables and graphs and tools such as flight computers (which until recently was nothing more than a specially marked circular slide rule) are taught to do the math and the trig.
But highly specialized pilots, particularly many test pilots, are highly educated engineers (or similar) and understand most if not all of the math underlying the design and operation of their craft. Those are likely to be the best sources of quality feedback to the design engineers regarding the performance of an aircraft and why it is not performing like it should and what changes might make it better.