No. I don't want its definition. I want to understand how we can't we can't do it in Multisim. Perhaps, I don't clearly understand hardware interfacing in this context.
I agree with chrisw1990. I think it is some sort of debugging. The way I read it is that you can simulate your design on the computer, build it, then see how it actually works with the computer connected to the build. To my knowledge Multisim doesn't do that last part, though you can capture images from a digital o-scope with one of the packages of Multisim.